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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DAG1
All Species:
6.06
Human Site:
S180
Identified Species:
13.33
UniProt:
Q14118
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14118
NP_004384.2
895
97441
S180
D
P
G
E
V
V
S
S
A
C
A
A
D
E
P
Chimpanzee
Pan troglodytes
XP_001164638
895
97501
S180
D
P
G
E
V
V
S
S
A
C
A
A
D
E
P
Rhesus Macaque
Macaca mulatta
XP_001108323
894
97378
A182
E
V
V
S
S
A
C
A
V
D
E
P
V
T
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62165
893
96886
A181
E
V
V
P
S
A
C
A
A
D
E
P
V
T
V
Rat
Rattus norvegicus
XP_343484
893
96688
A181
E
V
V
S
S
A
C
A
A
D
E
P
V
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509725
896
98376
G182
E
A
V
P
F
V
C
G
A
D
E
P
V
T
I
Chicken
Gallus gallus
NP_001091009
896
97593
G182
D
A
A
P
F
V
C
G
A
E
E
P
V
T
I
Frog
Xenopus laevis
NP_001082480
886
97556
D181
I
P
F
L
C
G
T
D
E
P
V
T
L
L
T
Zebra Danio
Brachydanio rerio
NP_775381
866
94555
C192
N
D
A
Q
P
F
I
C
G
N
E
E
P
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392358
704
79379
T80
T
T
T
T
T
T
T
T
P
A
P
T
S
A
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786589
869
94279
T186
D
A
D
W
S
L
L
T
P
Q
E
R
I
N
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.4
N.A.
N.A.
93.1
92.6
N.A.
85.4
77.7
68.9
60.8
N.A.
N.A.
20.6
N.A.
30
Protein Similarity:
100
99.4
98
N.A.
N.A.
95.8
95.3
N.A.
91.8
87.3
81
73.5
N.A.
N.A.
38.3
N.A.
48.7
P-Site Identity:
100
100
0
N.A.
N.A.
6.6
6.6
N.A.
13.3
20
6.6
0
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
13.3
N.A.
N.A.
20
20
N.A.
20
20
13.3
13.3
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
28
19
0
0
28
0
28
55
10
19
19
0
10
10
% A
% Cys:
0
0
0
0
10
0
46
10
0
19
0
0
0
0
0
% C
% Asp:
37
10
10
0
0
0
0
10
0
37
0
0
19
0
0
% D
% Glu:
37
0
0
19
0
0
0
0
10
10
64
10
0
19
0
% E
% Phe:
0
0
10
0
19
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
19
0
0
10
0
19
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
0
0
0
0
0
10
0
19
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
10
10
0
0
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% N
% Pro:
0
28
0
28
10
0
0
0
19
10
10
46
10
0
19
% P
% Gln:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
19
37
0
19
19
0
0
0
0
10
0
0
% S
% Thr:
10
10
10
10
10
10
19
19
0
0
0
19
0
46
19
% T
% Val:
0
28
37
0
19
37
0
0
10
0
10
0
46
10
28
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _